Analysis of Therapeutic Efficacy of Combination ofChemotherapy with OsteoblastPromoting and Anti-Osteolysis Agents on Bone Metastatic Carcinoma
10.3969/j.issn.0253-9896.2001.03.009
- VernacularTitle:促骨形成和抗骨吸收剂联合治疗骨转移癌效果分析
- Author:
Kai LI
;
Yan LIANG
;
Peng CHEN
- Publication Type:Journal Article
- From:
Tianjin Medical Journal
2001;29(3):154-156
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To estimate the clinical efficacy of combination of chemotherapy with osteoblast promoting and anti-osteolys-is agents in bone metastatic carcinoma. Methods: Seventy-one patients with bone metastatic carcinoma were divided into 2groups and treated with protocol A or B, respectively. The protocol A was a combination of chemotherapy with osteoblastpromoting and anti-osteolysis agents, the protocol B was a combination of chemotherapy with antiosteolysis agent only. Theefficacies of the 2 protocols were compared and studied. Results:The effect of A was more remarkable than that of B in re-lieving bone pain and enhancing bone repair. No severe adverse effect of these agents was found in therapy. Conclusion: Theclinical efficacy of combination of chemotherapy with osteoblast promoting and anti-osteolysis agents in bone metastatic car-cinoma was definite, the osteoblast promoting agent as an effective adjtmctive agent can be used not only in osteoprosis butalso in bone metastatic carcinoma.
