Application of T cell receptor rearrangement excision circles expression in allogeneic hematopoietic stem cell transplantation
10.3760/cma.j.issn.1009-9921.2009.12.022
- VernacularTitle:T细胞受体重排删除环检测在异基因造血干细胞移植中的应用
- Author:
Jufeng WU
;
Yangqiu LI
- Publication Type:Journal Article
- Keywords:
Receptors;
antigen;
T-cell;
Hematopoietic stem cell transplantation
- From:
Journal of Leukemia & Lymphoma
2009;18(12):763-765
- CountryChina
- Language:Chinese
-
Abstract:
Allogeneic hematopoietic stem cell transplantation(allo-HSCT) represents a potentially curative treatment modality in a range of hematologic malignancies and autoimmune disease. Immune reconstitution is a major factor to evaluate the outcome of transplantation.As markers for recent thymic output function,T cell receptor excision circles (TRECs) have been widely applied to evaluate thymie output function in normal individuals or in patients with hematopoietic stem cell transplantation, hematologic malignancies,HIV infection or autoinunune disease.
