Biological characteristics and molecular biology research hotspots of extranodal NK/T-cell lymphoma,nasal type
10.3760/cma.j.issn.1009-9921.2012.01.007
- VernacularTitle:结外鼻型NK/T细胞淋巴瘤生物学特征和分子生物学研究热点
- Author:
Bo CHEN
;
Yexiong LI
- Publication Type:Journal Article
- Keywords:
Lymphoma,extranodal NK-T-cell;
Cell line;
Genes;
Molecular biology
- From:
Journal of Leukemia & Lymphoma
2012;21(1):19-25
- CountryChina
- Language:Chinese
-
Abstract:
Extranodal NK/T-Cell lymphoma,nasal Type (NKTL) is an individual type in the World Health Organization (WHO) classification.The reports for NKTL are relatively uncommon since the incidence of this disease is low. In recent years, the nude mice model and cell lines of NKTL were established which built up the basis of researches in molecular biology. The investigation are carried out in molecular genetic analysis of lymphoproliferative disorders,tumor microenvironment,and target therapy and so on.We reviewed those advances and concentrated on the development of NKTL molecular biology.