Recent advances on diagnosis and therapy of chronic myelomonocytic leukemia
10.3760/cma.j.issn.1009-9921.2012.09.020
- VernacularTitle:慢性粒单核细胞白血病的诊治进展
- Author:
Deng PAN
- Publication Type:Journal Article
- Keywords:
Leukemia,myelomonocytic,chronic;
Molecular biology;
Hematopoietic stem cell transplantation;
Therapy
- From:
Journal of Leukemia & Lymphoma
2012;21(9):569-571
- CountryChina
- Language:Chinese
-
Abstract:
Chronic myelomonocytic leukemia (CMML) is a rare malignant disorder of hematopoietic system.It is classified by WHO as MDS/MPN and many gene mutations are invovled such as RAS,TET2 and CBL.Hypomethylating drugs are effective in the management of CMML and may alter the prognosis.Allogeneic stem cell transplantation is still the only way to cure the disorder.