Effect of mesenchymal stem cell in transplantation
10.3760/cma.j.issn.1009-9921.2009.06.021
- VernacularTitle:间充质干细胞在移植中的作用
- Author:
Jingjing TANG
;
Yanjuan LIN
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell transplantation;
Mesenchymal stem cells;
Graft versus host disease
- From:
Journal of Leukemia & Lymphoma
2009;18(6):373-376
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cell(MSC) is a kind of tissue stem cell having a characteristics of high self-renewal and multipotency. It is tended to be separated in vitro and play an important role in hematopoietic stem cell transplantation and transplantation of other systems. This article described mesenchymal stem cell's function and mechanism on supporting hematopoiesis, enhancing implantation,adjusting immunity and alleviating graft versus host disease (GVHD) in transplantation and also give some advices and experties about its further application.