Comparison of CT and dynamic-enhancement MRI for the diagnosis of hepatocellular carcinoma
- VernacularTitle:CT与MRI增强扫描诊断肝细胞癌的对比分析
- Author:
Gusheng XING
;
Shuang WANG
;
Han OUYANG
;
Xiaohong MA
;
Chunwu ZHOU
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Tomography,X-ray computed;
Magnetic resonance imaging;
Diagnostic imaging
- From:Chinese Journal of Medical Imaging Technology
2010;26(1):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the diagnostic ability of triple-phase CT and multiple-phase dynamic MR for patients with suspected hepatocellular carcinoma (HCC). Methods Triple-phase CT and multiple-phase dynamic MR scan were performed in 60 patients. Fifty-nine HCC lesions were confirmed in 39 patients. MR was performed with LAVA technique, the images included masks, dual-artery phases, dual-portal phases, dual-venous phases and delayed phase. Three observers separately evaluated the CT and MR imaging, and the results were compared with alternative-free-response ROC(AFROC)curve, the area under ROC (Az) was calculated to compare the diagnostic ability. Results The mean Az value of CT for the diagnosis of HCC was 0.8120±0.0118, of MR was 0.9093±0.0072 (P>0.05). In the group of HCC less than 1 cm in the diameter, the sensitivity of CT and MR was 63.89% and 80.55%(P＝0.013). In the groups HCCs of 1-3 cm and >3 cm, the sensitivity of CT and MR appeared no significant difference (P>0.05). Of all HCCs, the sensitivity of CT was lower than MR (83.62% vs 88.70%), but the difference was not significant (P>0.05). The positive predict value (PPV) of CT was also lower than MR (93.07% vs 96.31%, P>0.05). Conclusion The diagnostic ability of multiple-phase dynamic-enhancement MR scan for HCCs is similar to that of triple-phase enhancement CT. For HCC less than 1 cm in diameter, dynamic-enhancement MR is superior to that of contrast-enhancement CT scan, while for the larger ones, the difference is not significant.
