Development of chimerism study in hematopoietic stem cell transplantation
10.3760/cma.j.issn.1009-9921.2009.07.022
- VernacularTitle:嵌合体在非清髓性造血干细胞移植中的研究进展
- Author:
Li MA
;
Lieyang WANG
;
Liping SU
- Publication Type:Journal Article
- Keywords:
Chimerism;
Hematopoietic stem cell transplantation;
Transplantation immunology
- From:
Journal of Leukemia & Lymphoma
2009;18(7):441-443
- CountryChina
- Language:Chinese
-
Abstract:
Hematopoietic chimerism is a measure of the number of donor and recipient cells in the host following hematopoietic stem cell transplantation (HSCT), and it has a good correlation with GVHD and relapse. Chimerism detection after nonmyeloablative allo-HSCT is a simple essential and effective method to predict the outcome of the disease, and can significantly improve the success rate of transplants, reduce the recurrence and then improve the quanlity of life of patients.
