Pay attention to the long-term toxicities of therapy on lymphoma

VernacularTitle:应重视淋巴瘤治疗后的长期毒性
Author: Xia LIU ; Huaqing WANG
Publication Type:Journal Article
Keywords: Lymphoma; Antineoplastic combined chemotherapy protocols; Radiotherapy; Long-term toxicities
From: Journal of Leukemia & Lymphoma 2010;19(11):641-645
CountryChina
Language:Chinese
Abstract: There are an increasing number of survivors of successful treatment of lymphomas over the past 30 years. Although these survivors may be cured of their lymphoma, long-term morbidity and mortality are associated with late toxicities of the treatment. Identification of these late complications will lead to strategies to manage them when they occur and hopefully decrease the risk of their development. Secondary malignancies and treatment associated cardiovascular disease are the leading causes of late morbidity and mortality.Musculoskeletal difficulties, endocrine abnormalities, including sterility and thyroid disease, and heart and lung damage, have also been seen.The late complications of primary treatment of lymphoma and autologous stem cell transplantation usually for relapsed disease are the subjects of this paper.