Diagnosis and treatment of bone disease of multiple myeloma
10.3760/cma.j.issn.1009-9921.2010.07.021
- VernacularTitle:多发性骨髓瘤骨病的诊断与治疗新进展
- Author:
Jing WANG
- Publication Type:Journal Article
- Keywords:
Multiple Myeloma;
Osteopathic medicine;
Diagnosis;
Therapy
- From:
Journal of Leukemia & Lymphoma
2010;19(7):443-446
- CountryChina
- Language:Chinese
-
Abstract:
Up to 90 % of multiple myeloma patients can develop to osteolytic lesions. Although the conventional X radiography can only demonstrate the lytic bone disease when 30 % of the trabecular bone loss, it still remains the gold standard of the staging procedure of newly diagnosed myeloma patients. CT scans are more sensitive than X radiography for detecting small lytic lesions. MRI or CT is the choice of diagnosis to assess suspected cord compression. Technicium-99m bone scan in patients with myeloma usually underestimate the extent of bone damage. Treatments of myeloma bone disease include bisphosphonate therapy, novel targeted agents, surgical intervention and radiation therapy.
