Value of 99mTc-NOET and 99mTc-MIBI GSPECT in the diagnosis, treatment and prognosis of coronary artery disease
- VernacularTitle:99mTc-NOET和99mTc-MIBI门控心肌灌注显像在冠状动脉性心脏病诊疗和预后中的价值
- Author:
Yan CHENG
;
Sijin LI
;
Xianfeng LI
;
Zhifang WU
;
Haiyan LIU
- Publication Type:Journal Article
- Keywords:
Technetium Tc 99m,bis (N-ethoxy-N-ethyldithiocarbamato) nitrido-;
Technetium Tc 99m Sestamibi;
Gated myocardial perfusion SPECT imaging;
Angioplasty,transluminal,percutaneous coronary;
Coronary artery disease
- From:
Chinese Journal of Interventional Imaging and Therapy
2009;6(4):345-348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To predict the value of 99mTc-NOET gated myocardial perfusion SPECT imaging (GSPECT) in detecting coronary artery disease (CAD) and the theraputic effect of percutaneous transluminal coronary angioplasty (PTCA). Methods First, 70 patients suspected of CAD underwent 99mTc-NOET (group NOET1) or 99mTc-MIBI (group MIBI1) rest GSPECT and coronary angiography (CAG) was performed within 1 week after GSPECT. Second, 53 patients with CAD underwent 99mTc-NOET (group NOET2) or 99mTc-MIBI (group MIBI2) rest GSPECT before and 1, 3 and 6 months after PTCA and/or stent treatment. Results The sensitivity and specificity had no difference between group NOET1 and MIBI1 in detecting CAD. Comparison of group NOET 2 and MIBI 2: ①59.29%, 64.60% and 66.37% of the abnormal myocardial segment was improved in group NOET2.1, 3 and 6 months after PTCA, while 20.35%, 55.10% and 61.22% respectively in group MIBI2;②There was no difference of the incidence of clinical events and the myocardial function parameters before and after PTCA in group NOET2 and MIBI2. Conclusion Compared with 99mTc-MIBI, 99mTc-NOET has a greater clinical value for CAD diagnosis, PTCA efficacy and observation of the clinical events incidence.
