Thrombus formation in vivo
- VernacularTitle:活体血栓形成机理研究进展
- Author:
Li YANG
;
Yonggang LV
- Publication Type:Journal Article
- Keywords:
Thrombus;
Mechanism;
Thrombolitics;
Thrombogenesis;
Platelet aggregation;
Shear stress
- From:
Journal of Medical Biomechanics
2009;24(6):401-407
- CountryChina
- Language:Chinese
-
Abstract:
The mechanism of thrombus formation in living vessel wall is complex and involves a combination of blood and vessel wall properties and local flow conditions.The significance，theory and experimental tech-niques of thrombus formation in vivo were comprehensively reviewed.Particularly,the important role of signa-ling pathway and hemodynamic in thrombus formation in vivo was pointed out.The difficulty ic in vivo animal models was analyzed.Some recent new phenomena as welt as new approaches and directions worthy of in-vestigation also were summarized.
