Peri-operative CT perfusion imaging after living liver transplantation
10.3321/j.issn:1003-3289.2009.10.023
- VernacularTitle:活体肝移植术后围手术期CT灌注成像
- Author:
Xiaoyan WANG
;
Lijun QIAN
;
Jianrong XU
- Publication Type:Journal Article
- Keywords:
Tomography;
X-ray computed;
Perfusion;
Living donors;
Liver transplantation;
Hyperemia
- From:
Chinese Journal of Medical Imaging Technology
2009;25(10):1813-1816
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare CT perfusion changes of patients 1 month after living liver transplantation with healthy volunteers. Methods Twenty perioperative patients without complications and 25 healthy volunteers underwent dynamic multi-slice CT scan. On each targeted slice, liver was divided into 3 regions of interest (ROI) according to hepatic venous drainage, i.e. anterior segment area drained by middle hepatic veins (MHV) which was most likely congested, risk area drained by both MHV and RHV which was posterior to anterior segment, reference area drained by RHV. Perfusion parameters and relative perfusion difference were calculated.Results The relative perfusion differences of anterior segment and risk area in study group were as follows: BF 44.56±43.19 vs 25.41±27.49 [ml/(min〖DK〗·100 g)]; BV 3.91±2.45 vs 2.15±1.86(ml/100 g); PVP 41.50±39.15 vs 22.66±23.82 [ml/(min·100 g)]. Significant differences of RPDs of BF, BV and PVP were found in anterior segment (P<0.0001) and risk area (P<0.01) compared with control group.Conclusion In perioperative period, there are hemodynamic differences in hepatic segments drained by RHV and MHV. BF, BV, PVP of anterior segment decreases obviously.