Transrectal contrast enhanced ultrasound in distinguishing benign from malignant nodes of prostate
10.3321/j.issn:1003-3289.2009.10.038
- VernacularTitle:经直肠超声造影鉴别诊断前列腺良、恶性结节
- Author:
Yueqin ZHA
;
Weidong SHEN
;
Weiguo CHEN
;
Heping LIN
;
Lingling SHEN
;
Zongqiang CAI
;
Xiaofeng CAI
;
Jianquan HOU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
high-intensity focused;
transrectal;
Prostate;
Contrast media
- From:
Chinese Journal of Medical Imaging Technology
2009;25(10):1867-1870
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate diagnostic value of transrectal gray scale contrast enhanced ultrasound (CEUS) in distinguishing benign from malignant nodes of prostate. Methods Thirty-three patients with 38 prostate nodes underwent real-time transrectal gray scale CEUS with SonoVue and contrast pulsed sequence (CPS). Contrast enhancement pattern of the prostate nodes were recorded and time-intensity curves (TIC) were drawn to calculate the parameters and difference between benign and malignant nodes. Results Twenty benign nodes (17 in inner gland) and 18 malignant ones (14 in external gland) were confirmed by pathology. Compared with normal peripheral zone, malignant lesions showed significantly earlier time to enhancement. The time to peak (TTP), accelerating time (ACT) and peak intensity (PI) of malignant lesions were lower than those of benign lesions (P<0.05).There was no significance in arrival time (AT) between the two groups (P>0.05). Conclusion Of all parameters in CEUS, TTP, ACT and PI are different between prostate benign and malignant lesions, and thus contribute to discriminate prostate cancer from benign diseases.
