Research progress of MCL-1 gene
10.3760/cma.j.issn.1009-9921.2011.09.021
- VernacularTitle:髓系白血病-1的基因研究进展
- Author:
Yujie GUO
- Publication Type:Journal Article
- Keywords:
Leukemia,myeloid;
Apoptosis;
Genes;
Research
- From:
Journal of Leukemia & Lymphoma
2011;20(9):569-571
- CountryChina
- Language:Chinese
-
Abstract:
MCL-1 gene is a antiapoptotic gene belong to BCL-2 gene family, its product MCL-1 protein plays an important role in cell apoptosis regulating and the course of hematologic malignancies.This paper reviews advance of studies on the function of MCL-1 gene and MCL-1 protein,the role of MCL-1 protein in hematologic malignancies and the relationship between MCL-1 protein and other apoptosis adjustment factors.
