Effects of all tram retinoic acid on CD106 and CD54 expression in human bone marrow mesenchymal stem cells in vitro
10.3760/cma.j.issn.1009-9921.2008.03.001
- VernacularTitle:全反式维甲酸对人类骨髓间充质干细胞CD106、CD54表达影响的体外研究
- Author:
Junling TANG
;
Li ZHANG
;
Ting LIU
;
Xiaoming LI
- Publication Type:Journal Article
- Keywords:
Tretinoin;
Mesenchymal stem cell;
Cell adhesion molecule
- From:
Journal of Leukemia & Lymphoma
2008;17(3):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of all trans retinoic acid (ATRA) on the expression of CD106 and CD54 in human bone mesenchymal stem cells and cell growth curve in vitro. Methods The expression of CD54 and CD106 of human BM-MSC was detected by flow cytometry, and cell growth curve of human BM-MSC was tested by MTT assay after coculturing with 0.01, 0.1, 1.0 and 10.0 μmol/l ATRA, respectively. Results The expression of CD54 and CD106 is increased by 0.01, 0.1, 1.0 and 10.0 μmol/1 ATRA in vitro. Conclusion The expression of CD54, and CD106 of human BM-MSC was up-regulated by ATRA.
