Advanced development of dendritic cell and leukemia
10.3760/cma.j.issn.1009-9921.2009.02.022
- VernacularTitle:树突状细胞与白血病研究进展
- Author:
Fuming ZI
;
Guohe WU
- Publication Type:Journal Article
- Keywords:
Dendritic cell;
Leukemia;
Antigen
- From:
Journal of Leukemia & Lymphoma
2009;18(2):123-127
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells are the most powerful cells to induce T cell immune reaction. DC derived from leukemia also possess the ability of the antigen processing and presentation. DC pulsed with tumor antigen can effectively initiate T cell immune reaction and induce T cell to cytotoxic T lymphocytes in vitro and in vivo. In this text, we introduce the advanced development of the biological character of DC, tumor immunology, the mechanism of tumor cell escaping immune surveillance and DC in leukemia immunotherapy.
