Measurement of Cerebral Perfusion by Dynamic CT: Preliminary Application
10.3321/j.issn:1003-3289.2001.02.015
- VernacularTitle:动态CT脑血流灌注测量及临床初步应用
- Author:
Peiyi GAO
;
Yan LIN
;
Hongmei ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of Medical Imaging Technology
2001;17(2):153-135
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical measurement of cerebral perfusion by dynamic CT. Methods Thirteen normal adults were examined by dynamic CT for the measurement of cerebral blood flow (CBF). Another dynamic CT scans with the measurement of CBF were performed separately to rule out cerebral ischemia in 5 cases and secondary Parkinson disease in 2. Results Normal cerebral cortical perfusion was measured at 59.3~96.8 ml*min-1*100g-1 with the mean value 76.2 ml*min-1*100g-1. Normal white matter perfusion was measured at 27.1~43.1 ml*min-1*100g-1 with the mean value 33.9 ml*min-1*100g-1. In 5 cases of suspending cerebral ischemia, one showed increase of CBF and 4 presented decrease of CBF. In 2 cases of suspending secondary Parkinson disease, one appeared decrease of CBF and other one was normal. Conclusion Dynamic CT scan with the measurement of CBF can demonstrate the hemodynamic status of normal brain and pathological lesion. Combined with routine CT scan, measurement of cerebral perfusion by dynamic CT is an ideal method to show the morphological and functional changes of brain tissue simultaneously.