Clinical Effects of Urokinase in Combination with Heparin Sodium in 50 Patients Suffer from Acute Cerebral Infarction
10.3321/j.issn:1003-3289.2001.03.013
- VernacularTitle:尿激酶、肝素联合应用治疗进展型脑梗塞50例临床观察
- Author:
Fengqing GAO
;
Wenfu LU
;
Xiuying LI
- Publication Type:Journal Article
- From:
Chinese Journal of Medical Imaging Technology
2001;17(3):223-224
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To assess the clinical efficacy and safety of acute cerebral progressive infarction cured with urokinase in combination with heparin sodium. Methods There were 50 cases in the control group and treated group. The treated group was treated with urokinase 300,000 units/day intravenous for 1～2 days, heparin sodium 12,500 units/day intravenous for 5 days, the control group was treated with heparin sodium 12,500 units/day intravenous for 5 days. All patients were treated within 5 days of onset and the deterioration of neurological deficits within 10 hours. The hypodensity was showed by brain CT scan without hemorrhage, MDS score was given before and after cure 30 days for comparison. Results The neurological deficits improvement in the treated group was more efficient than the control group and no hemorrhage was found. Conclusion Middle dose urokinase infusion in combination with heparin sodium intravenous in treatment of acute cerebral progressive infarction was safe and effective and showed obviously clinical valuable.
