The Implication of Ionic Contrast Media Made in China in Contrast-Enhanced CT

VernacularTitle:国产离子型对比剂在CT增强扫描中的应用
Author: Jianbo GAO ; Hua GUO ; Xuehua YANG
Publication Type:Journal Article
From: Chinese Journal of Medical Imaging Technology 2001;17(3):283-285
CountryChina
Language:Chinese
Abstract: Purpose　To evaluate the clinical safety of ionic contrast media made in china and compare with nonionic contrast media being imported. Methods　Among contrast-enhanced CT 1096 cases, 76% meglumine diatrizoate were administed in 864 cases and ultravist in 232 cases , comparative studies on adverse drug reactions(ADRs) and image quality were performed. Results　In 76% meglumine diatrizoate group , the prevalence of overall and mild -middle ADRs was higher than in the ultravist group , the prevalence of severe and potentially life-threatening ADRs was approximate in the ultravist group , the image quality was well than in the ultravist group.Preventive inoculation alleviated ADRs at all levels. Conclusion　Ionic contrast media made in china was safe and effective in patients without hyperthyroidism after preventive inoculation.