MicroRNAs as a potential biomarker for central nervous system injury diagnosis
10.3760/cma.j.issn.1009-9158.2015.03.017
- VernacularTitle:中枢神经系统损伤潜在标志物microRNAs的研究进展
- Author:
Jiaxi SONG
;
Dongmei NIU
;
Junjun WANG
- Publication Type:Journal Article
- Keywords:
microRNAs;
Brain ischemia;
Brain injuries;
Spinal cord injuries;
Biological markers
- From:
Chinese Journal of Laboratory Medicine
2015;(3):211-214
- CountryChina
- Language:Chinese
-
Abstract:
Central nervous system ( CNS) injuries, such as cerebral ischemia, traumatic brain injury (TBI), and spinal cord injury (SCI), are often accompanied by complex pathological changes, and could lead to a variety of other neurological diseases.Neurons and glial cells are precisely regulated by many genes.MicroRNA ( miRNA ) are endogenous molecules discovered in recent years that regulate post transcriptional gene expression.They are highly expressed in the central nervous system and abnormal expressed under pathological conditions.They are involved in regulating variety of pathological processes after CNS injuries, and are CNS disease potential biomarkers.
