Clinical observation of iron removal treatment with week-therapy of chronic iron overload
10.3760/cma.j.issn.1009-9921.2013.08.012
- VernacularTitle:周疗法去铁治疗慢性铁超负荷的临床观察
- Author:
Ting WANG
;
Yanjun WANG
;
Linli PAN
;
Jie WU
;
Lei ZHANG
;
Yini GUO
- Publication Type:Journal Article
- Keywords:
Iron overload;
Ferritins;
Blood transfusion;
Week therapy;
Iron removal treatment;
Liver function
- From:
Journal of Leukemia & Lymphoma
2013;22(8):491-493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical application and curative effect of iron removal treatment with week-therapy in chronic iron overload related to blood transfusion.Methods Twenty patients who were diagnosed as chronic iron overload were retrospectively studied.The amelioration of liver and pancreatic fanctions in patients with chronic iron overload treated with week-therapy of iron chelating agent through intravenous drip.Results The changes in the level of serum ferritin [2693.7±709.9) μg/L] were not significant after treatment at six months,hut the cilinical symptoms were relieved obviously.The levels of serum ferritin in patients after the treatment at twelve months were significantly different from the level before treated [(2083.7±714.4) μg/L vs (2771.5±725.2) μg/L,t =3.35,P ＜ 0.01],and the decreases were significant in sixteen patients.The liver functions in seven patients were improved and pancreatic functions were better in five patients.Conclusion The study suggests that iron removal treatment with week-therapy is effective for chronic iron overload,and improves the functions of damaged organs.
