The Role of Plasma Endothelin in Patients with Migraine
10.3969/j.issn.0253-9896.2000.11.007
- VernacularTitle:偏头痛与血浆内皮素
- Author:
Junshan ZHOU
;
Zushun CHEN
- Publication Type:Journal Article
- Keywords:
migraine endothelins
- From:
Tianjin Medical Journal
2000;28(11):660-661
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between plasma endothelin and migraine attack. Methods:The plasma endthelin(ET-1) levels were measured by radioimmunoassay in 54 patients with migraine ( classic: 18, common:36 ) and 20 patientsvith tension headache. Results:The plasma ET-1 level in patients with migraine attack was higher than that of normal con-trols or patients with tension headache (P <0.01). During intermission, the ET-1 level of patients with classic migraine washigher than that of patients with common migraine (P <0.01),and the ET-1 level in male patients was higher than in fe-male ones. Conclusion: The data suggest that there are abnormalities of vascular endothelial cell system in patients with mi-graine. ET-1 may be one of factors causing migraine attack.