A Study of HLA Antigens in Behcet's Syndrome.
10.3349/ymj.1988.29.3.259
- Author:
Sungnack LEE
1
;
Young Jin KOH
;
Duck Hyun KIM
;
Dongsik BANG
;
In Whan NAM
;
Kwang Hoon LEE
;
Kiil PARK
Author Information
1. Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Behcet's syndrome;
HLA typing
- MeSH:
Adolescent;
Adult;
Behcet Syndrome/*immunology;
Female;
HLA Antigens/*analysis/classification;
Human;
Korea;
Male;
Middle Age;
Support, Non-U.S. Gov't
- From:Yonsei Medical Journal
1988;29(3):259-262
- CountryRepublic of Korea
- Language:English
-
Abstract:
Fifty-two Korean patients with Behcet's syndome were typed for HLA antigens. 52 apparently healthy Korean subjects were used as controls; 42 for HLA-A, B, C and all 52 for HLA-DR typing. HLA-B5 and DRw8 presented significantly high frequencies in all patiens. According to Shimizu's classification, HLA-B5 and DRw8 were significantly increased in the complete type; B5 in the incomplete type; DR3 in the suspected-possible type. According to Lehner's classification, HLA-DR3 was significantly increased in the neurological type; B5 in the ocular type; B5 in the ocular type. We confirmed the association of HLA-B5 with the severity of Beh et's syndrome. A relation might exist between DRw8, DR3 and Behcet's syndrome.
