Aplastic Anemia Associated with Stomach.
10.3349/ymj.1988.29.3.263
- Author:
Jee Sook HAHN
1
;
Doe Young KIM
;
Dong Ki NAM
;
Young Sik LEE
;
Sun Ju LEE
;
Yun Woong KO
;
Chang Hwan CHO
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Aplastic anemia;
stomach cancer;
surgery
- MeSH:
Adenocarcinoma/*complications/secondary/surgery;
Anemia, Aplastic/*complications/drug therapy;
Case Report;
Human;
Male;
Middle Age;
Oxymetholone/therapeutic use;
Stomach Neoplasms/*complications/surgery
- From:Yonsei Medical Journal
1988;29(3):263-269
- CountryRepublic of Korea
- Language:English
-
Abstract:
Herein is presented a case of aplastic anemia associated with adenocarcinoma of the stomach which seem- ed to be coincidental. A 52 year-old man was admitted with a 3 year history of dyspnea. Three years previously, he was diagnosed as bone marrow hypoplasia and had been treated with oxymetholone for 1 year. After confirmation of aplastic anemia during the first admission, he was followed up with fluoxymesterone and steriods. One year later, he was readmitted with melena. Fibergastroscopy and an UGl study revealed a fungating mass on the antrum suggestive of stomach cancer. Following perioperative platelet transfusions and intensive supportive care, a subtotal gastrectomy was performed and there were no postoperative complications. Pathologic examinations disclosed a moderately well differentiated adenocarcinoma. This is the first report in Korea of adenocarcinoma of the stomach occurring in a patient with aplastic anemia. He survived 17.5 months after the surgery and 5.4 years after the onset of aplastic anemia. Gastrointestinal bleeding in aplastic anemia may be incorrectly ascribed to steriod use and overlooked, thus the need to fully investigate gastric pathology by endoscopy as well as radiology is streesed. In a patient with pancytopenia, the major surgical procedures are frequently evaded by both surgeons and internists due to the possibility of morbidity from bleeding and infection. In this case, intensive perioperative supportive care and surgery were combined to prolong the patient's survival time.
