A Case of Vitamin B12 Deficiency Megaloblastic Anemia Following Total Gastrectomy.
10.3349/ymj.1988.29.3.270
- Author:
Jee Sook HAHN
1
;
Dong Ki NAM
;
Eun Jig LEE
;
Sun Ju LEE
;
Yun Woong KO
;
Il Nam SUNWOO
;
Kyong Sik LEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report ; Review
- Keywords:
Megaloblastic anemia;
total gastrectomy;
neuropathy;
intrinsic factor;
vitamin B12 deficiency
- MeSH:
Anemia, Macrocytic/*etiology;
Anemia, Megaloblastic/diagnosis/*etiology;
Case Report;
Gastrectomy/*adverse effects;
Human;
Male;
Middle Age;
Vitamin B 12 Deficiency/*etiology
- From:Yonsei Medical Journal
1988;29(3):270-277
- CountryRepublic of Korea
- Language:English
-
Abstract:
Megaloblastic anemia following gastrectomy is due to the total absence or inadequate secretion of intrinsic factor and is manifested by megalobastic changes in bone marrow, blood cells, and other proliferative cells. In Korea, detailed description and precise analyses of the cases of megaloblastic anemia following gastrectomy are relatively rare in contrast to the potential of its incidence from gastrectomy due to many causes or to the importance of its clinical significance. Here, we present the case of a 51-year old man who had undergone a total gastrectomy with esophagojejunostomy and incidental splenectomy due to early gastric cancer and developed megalobastic anemla 7 years after surgery. After gradual improvement of clinical and hematologic features with treatment of parenteral vltamin Bl2, he was followed-up with vitamin B12 maintenance therapy.
