Analysis of precancerous conditions and lesions of high-risk population in the high-incidence area of esophageal cancer in Ci County
10.3969/j.issn.1000-8179.20140853
- VernacularTitle:磁县食管癌高发区高危人群食管癌前状态及病变分析
- Author:
Guohui SONG
;
Fanshu MENG
;
Wenlong BAI
;
Guoliang JIN
;
Dongfang LI
- Publication Type:Journal Article
- Keywords:
esophageal neoplasms;
precancerous conditions;
risk population;
early detection;
screening
- From:
Chinese Journal of Clinical Oncology
2014;(19):1259-1263
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the distribution of precancerous conditions and lesions of high-risk population in the high-in-cidence area of esophageal cancer in Ci County, Hebei Province. Methods:Esophageal cancer was detected early in 40 to 69 year old patients in Ci Xian through endoscopic screening data and endoscopic screening using iodine staining and indicative biopsy. The pa-tients were classified according to gender, age group, statistical esophageal precancerous condition, and lesion detection rate. Results:The analysis included 11 423 cases by screening queue, and the esophageal biopsy rate was 66.90%. The detection rates of squamous epithelium with mild, moderate, and severe dysplasia were 11.84%, 2.66%, and 1.04%, respectively. DCIS detection rate was 0.40%in patients with squamous cell carcinoma. The detection rate of the patients had been infiltrated by the squamous cell carcinoma was 0.04%.The rate of the squamous cell carcinoma within the mucosa was 0.37%.The rate of the infiltration squamous cell carcinoma was 0.17%. The detection rate of the hyperplasia above average severe dysplasia and cancer was 2.01%. Conclusion: High incidence of esophageal precancerous lesions was found in the Ci County aged 40 to 69. A large number of asymptomatic patients with cancer were detected. Age and sex are closely related to detection rate.
