Characterization of circulating microRNA and its clinical application
10.3760/cma.j.issn.1009-9158.2014.12.023
- VernacularTitle:循环microRNA的特性及其在肿瘤中的应用
- Author:
Yujuan ZHANG
;
Sha GUO
;
Wei CUI
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Tumor markers,biological;
Reverse transcriptase polymerase chain reaction
- From:
Chinese Journal of Laboratory Medicine
2014;37(12):964-968
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are small noncoding regulatory RNAs ranging in size from 17 to 25 nucleotides which participate many physiological and pathological processes.MicroRNA could also stably exist in peripheral blood,and the detection of circulating microRNA is of great significance for disease diagnosis and prognosis.As so far,there is no unified method and standard for detection of microRNA,which is the major reason for discrepant results between different studies.However,circulating microRNA,as a new disease detection biomarker,has stable properties,convenient detection and high accuracy features,so it till has an important potential value in clinical applications.
