Progression of targeted therapy of multiple myeloma bone disease
10.3760/cma.j.issn.1009-9921.2011.06.015
- VernacularTitle:多发性骨髓瘤骨病的靶向治疗进展
- Author:
Tianmei ZENG
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Osteopathic medicine;
Cytokines;
Targeted therapy
- From:
Journal of Leukemia & Lymphoma
2011;20(6):382-384
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma (MM) is a hematological malignancy. Osteolytic lesion is the commonest complication in patients with MM. Skeletal-related events severely affect the survival quantity and prognosis. Current therapeutic approach for the treatment of myeloma bone disease (MBD) is based on the use of bisphosphonates. AS the recent advance in the pathogenesis and therapeutics of MBD,more factors related to this disease are found. In this article important factors related to the pathogenes of MBD and the cytokine targeted therapies are reviewed.
