Application of color Doppler ultrasonography in the acute rejection of renal transplantation
10.3321/j.issn:1003-3289.2009.07.035
- VernacularTitle:彩色多普勒超声在移植肾急性排异反应中的应用
- Author:
Hongchun ZENG
;
Yihan RE
;
Yingxin WANG
;
Lanhui YAO
- Publication Type:Journal Article
- Keywords:
Ultrasonography,Doppler,color;
Kidney transplantation;
Graft rejection;
Sensitivity;
Specificity
- From:
Chinese Journal of Medical Imaging Technology
2009;25(7):1245-1247
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find the spectacular indexes in the diagnosis of acute rejection of renal transplantation with color Doppler ultrasonography. Methods Forty-two patients with renal rejection were confirmed with percutaneous needle biopsy and 115 patients with stable renal function were confirmed with following-up (>1 year) and clinical examination. The length, width, thickness, cortex thickness and resistive index (RI) of two groups were analyzed statistically. Then the specificity, sensitivity, misdiagnosis rate, false negative rate and consistency rate of renal volume, pyramid swelling, echo weakening, RI<0.7, RI≥0.7 and RI≥0.8 were calculated. Results The length, width and thickness were statistically different in two groups (P<0.05). In patients with renal rejection, the marginal blood vessels in renal cortex decreased, and the blood velocity reduced obviously in the diastolic phase and RI increased obviously (P<0.05). The sensitivity of the above indexes were 55.30%, 55.20%, 42.10%, 57.90%, 31.60%, respectively, while the specificity were 71.30%, 87.10%, 25.70%, 74.20% and 98.20%, respectively. Conclusion Enlargement of renal volume, swelling of renal pyramids, echo weakening and RI increasing are specific indexes for diagnosis of acute rejection of renal transplantation.