Diffusion weighted imaging in the evaluation of therapeutic effect of endocrine for prostate cancer with bone metastases
10.3321/j.issn:1003-3289.2009.10.029
- VernacularTitle:磁共振扩散加权成像在评价前列腺癌骨转移病灶内分泌治疗效果中的价值
- Author:
He WANG
;
Xiaoying WANG
;
Feiyu LI
;
Xuemei GUO
;
Xuexiang JIANG
- Publication Type:Journal Article
- Keywords:
Prostate neoplasms;
Bone metastasis;
Magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2009;25(10):1833-1836
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect of endocrine for prostate cancer with bone metastases with MR diffusion-weighted imaging (DWI). Methods Forty patients with bone metastases from prostate cancer were examined with DWI. Seventeen patients underwent endocrine therapy were recruited as the test group, the other 23 were regarded as the control group. There was no relapse of the metastases according to clinical diagnosis in the test group. DWI sequences were based on steady-state free precession with b value (800 s/mm~2). After identifying the metastasis according to the T1WI and T2WI, ROIs were marked at the metastases, normal muscle, normal bone and bladder on DWI, and the ADC values of the ROIs were calculated respectively. Non-parameter two independent samples test was applicated to compare the ADC values of the metastases between the two groups.Results ADC values of the bone metastases were (1.10±0.50)×10~(-3)mm~2/s in the test group and (1.12±0.30) ×10~-3mm~2/s in the control group (P>0.05).Conclusion MR DWI shows no help in evaluating the therapeutic effect of endocrine for prostate cancer with bone metastases.
