Effect of treatment by bortezomib together with dexamethsone to the refractory multiple myeloma
10.3760/cma.j.issn.1009-9921.2008.05.015
- VernacularTitle:硼替佐米治疗难治性复发性多发性骨髓瘤疗效分析
- Author:
Juan HE
;
Jie LI
;
Xiaoyi Lü
;
Baixun WANG
;
Ming ZHAI
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Drug therapy,combination;
Bortezomib;
Dexamesathone
- From:
Journal of Leukemia & Lymphoma
2008;17(5):359-360
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of bortezomib together with dexamethsone on the treatment of refractory multiple myeloma.Methods Bortezomib at 1.3 mg/m2 iv drop 1 d,4 d,8 d,11 d.Dexamethasonc 20 mg/d,1～4 d,8～11 d,17～20 d.21 days are used as a course.For bi-course dexamethasone was given by 20 mg/d,at 1～4 d.Results After 2～6 periods,3 cases achieved completely recovery(CR),4 cases are near to completely recovery(CR),3 cases got partially recovery(PR).Conclusion It is a good choice to treat refractory multiple myeloma by Bortezomib together with dexamethagone.
