Glassy carbon electrode modified with multi-walled carbon nanotubes sensor for the quantification of antihistamine drug pheniramine in solubilized systems
10.1016/j.jpha.2011.09.013
- Author:
Rajeev JAIN
;
Sanjay SHARMA
- Publication Type:Journal Article
- Keywords:
Pheniramine;
Sodium lauryl sulfate (SLS);
Glassy carbon electrode modified with multi-walled carbon nanotubes (GCE-MWCNTs);
Solubilized systems;
Voltammetric quantification
- From:
Journal of Pharmaceutical Analysis
2012;02(1):56-61
- CountryChina
- Language:Chinese
-
Abstract:
A sensitive electroanalytical method for quantification of pheniramine in pharmaceutical formulation has been investigated on the basis of the enhanced electrochemical response at glassy carbon electrode modified with multi-walled carbon nanotubes in the presence of sodium lauryl sulfate.The experimental results suggest that the phcniramine in anionic surfactant solution exhibits electrocatalytic effect resulting in a marked enhancement of the peak current response.Peak current response is linearly dependent on the concentration of pheniramine in the range 200-1500 μg/mL with correlation coefficient 0.9987.The limit of detection is 58.31 μg/m L.The modified electrode shows good sensitivity and repeatability.
