Research advances on cytogenetic and molecule mechanism of acute megakaryoblastic leukemia
10.3760/cma.j.issn.1009-9921.2009.01.021
- VernacularTitle:急性巨核细胞白血病细胞遗传学及分子机制研究进展
- Author:
Ting WANG
;
Rong FU
- Publication Type:Journal Article
- Keywords:
Leukemia,acute,megakaryoblastic;
Cytogeneties;
Pathogenesis
- From:
Journal of Leukemia & Lymphoma
2009;18(1):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Acute megakaryoblastic leukemia(AML-M7)is a rare neoplastic hematologic disorder,the pathogenesis is not clearly.Recent research has found many eytogenetic changes in this disease;and also some genes mutation,such as GATAI,p53,RUNXI play very important roles in AMKL.The aim of this article is to review the cytogenetic and molecule mechanism of acute megakaryoblastic leukemia.
