Study on factors associated with long-term survival of acute leukemia

VernacularTitle:急性白血病长期生存相关因素研究
Author: Weidong SHU ; Chucheng WAN ; Yunjin XIA ; Zhenghua ZHANG
Publication Type:Journal Article
Keywords: Leukemia; Therapy; Disease-free survival
From: Journal of Leukemia & Lymphoma 2009;18(12):739-741
CountryChina
Language:Chinese
Abstract: Objective To analyze factors associated with long-term survival of acute leukemia(AL). Methods Clinical data is analyzed in 27 leukemia cases who had at least 5 years free survival (EFS). Combined intensive chemotherapy was administered under the principle of individualization to induce remission.Regular consolidation treatment after remission was strictly continued.Long-term follow up Was kept on,with the therapeutic regimen modified accordingly.Results Complete remission(CR) was achieved in 112 of 143(78.3%)AL patients and 27(18.9%)of them had survived more than 5 years.Conclusion The long-term survival of AL patients is related to the type of AL,leukemia cell burden,extramedullary leukemia, individual treatment,time required to achieve CR,continuous intensive chemotherapy and the regular postremission treatment.