Effects of Herb-partitioned Moxibustion and Electroacupuncture on Serum Indexes of Intestinal Fibrosis in Rats with Crohn's Disease
10.1007/s11726-011-0460-1
- VernacularTitle:隔药灸和电针对大鼠克罗恩病肠纤维化血清学指标的影响
- Author:
Yanbo REN
;
Cuihong ZHANG
;
Caiping AN
;
Huangan WU
;
Jue HONG
;
Lingxiang WU
;
Jie LIU
;
Xiaopeng MA
;
Zhen WANG
- Publication Type:Journal Article
- Keywords:
Indirect Moxibustion;
Electroacupuncture;
Crohn Disease;
Fibrosis;
Serology
- From:
Journal of Acupuncture and Tuina Science
2011;09(1):13-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the impact of herb-partitioned moxibustion and electroacupuncture on hyaluronic acid(HA),procollagen Ⅲ(PC Ⅲ)and collagen Ⅳ(CⅣ)of intestinal fibrosis in rats with Crohn's disease(CD),and discuss the effect and the mechanism of acupuncture on treating intestinal fibrosis of rats.Methods:SD rats were randomly divided into control group,model group,herb-partitioned moxibustion group,electroacupuncture group and medicine group.The model of CD was developed by trinitrobenzene sulfonic acid.Masson stain was used to observe the collagen fibers hyperplasia in colon and radioimmunoassay was adopted to detect the content of HA,PC Ⅲ and C Ⅳ in serum.Results:Compared with the control group,the proliferation of colonic collagen fibers,as well as the HA,PC Ⅲ and CⅣ in serum increased in the model group.Compared with the model group,the expression of collagen fibers,serum HA,PC Ⅲ and C Ⅳ decreased in the herb-partitioned moxibustion group,electroacupuncture group and medicine group.The expression of collagen fibers serum HA,PC Ⅲ and C Ⅳ in the herb-partitioned moxibustion group were lower than in the electroacupuncture group and medicine group.Conclusion:Herb-partitioned moxibustion and electroacupuncture effectively improved the pathological state of intestinal fibrosis in rats with CD and reduced the content of HA,PC Ⅲ and C Ⅳ in serum.
