Effect of Suhuangzhike Capsule on eosinophilia and exhaled nitric oxide in patients with cough variant asthma
10.3760/cma.j.issn.1008-6706.2015.09.005
- VernacularTitle:苏黄止咳胶囊对咳嗽变异性哮喘患者血嗜酸性粒细胞和呼出气一氧化氮的影响
- Author:
Liqin WANG
- Publication Type:Journal Article
- Keywords:
Cough variant asthma;
Suhuangzhike capsules;
Eosinophils;
Fractional exhaled nitric oxide
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;22(9):1294-1296
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effectiveness of Suhuangzhike Capsule on eosinophilia (Eos) and exhaled nitric oxide (FeNO) in patients with cough variant asthmathe.Methods 98 patients with cough variant asthmathe were randomly divided into the two groups,the control group (n =49 cases) and the observation group (n =49 cases).The patients in the control group were treated through the conventional treatment,while the patients in the observation group were treated through the conventional treatment plus Suhuangzhike Capsule.They were treated for four weeks.Eos and FeNO were detected before and after treatment.Results The total effective rate of the control group was 87.8％,which of observation group was 95.9％;The total effective rate of the observation group was obviously higher than that of the control group (x2 =4.86,P ＜ 0.05).The two groups after treatment the blood Eos and FeNO were significantly lowered (t =5.102,8.772,7.921,10.224,P ＜ 0.05,P ＜ 0.01).And compared with the control group after treatment,the patients in the observation group decreased more significantly (t =2.714,3.336,all P ＜ 0.05).Conclusion Suhuangzhike Capsule can decrease eosinophilia and exhaled nitric oxide in patients with cough variant asthmathe.
