Meta-analysis of the use of propofol as a sedative agent in gastrointestinal endoscopy
10.3760/cma.j.issn.1672-7088.2014.32.015
- VernacularTitle:丙泊酚与传统麻醉剂用于成人胃肠镜检查效果比较的Meta分析
- Author:
Qing NIU
;
Zongmei ZHANG
;
Shuju CHEN
- Publication Type:Journal Article
- Keywords:
Propofol;
Gastrointestinal endoscopy;
Meta analysis
- From:
Chinese Journal of Practical Nursing
2014;30(32):48-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the efficacy and safety of propofol sedation for gastrointestinal endoscopy,we conducted a Meta-analysis of randomized controlled trials (RCT) comparing propofol with traditional sedative agents.Methods Referring Cochrane Collaboration search strategy to develop retrieval in Medline,Web of Science,Wanfang and CNKI database to retrieve the anesthetic propofol and traditional agents in the literature for randomized controlled trials of gastrointestinal endoscopy,surgery and assess their recovery effect.Results Twenty-one original RCTs investigating a total of 1 765 patients,of whom 894 received propofol only and 871 received traditional sedative agents only,met the inclusion criteria.Research showed that compared with traditional anesthetics,no significant differences existed in anesthetic effects of propofol on gastrointestinal endoscopy surgery time.However,surgery can significantly shorten recovery time and the average discharge time; and higher recovery rates.The result of racial subgroup analysis showed:the anesthetic propofol can significantly shorten the time of gastrointestinal endoscopy surgery for Asian populations,but had little effect on the European population.Contrast method for subgroup analysis showed:anesthetic propofol could significantly shorten the ERCP angiography in gastrointestinal endoscopy surgery time,but has little effect on the UGE and colonscopy angiography.Conclusions Propofol is safe and effective for gastrointestinal endoscopy procedures and is associated with shorter endoscopy recovery and discharge time,higher post-anesthesia recovery scores.Care should be taken when extrapolating our results to specific practice settings and high-risk patient subgroups.
