Advances of Wnt/β-catenin signal pathway in breast cancer
10.3760/cma.j.issn.1673-4203.2015.03.023
- VernacularTitle:Wnt/β-catenin信号通路在乳腺癌中的研究进展
- Author:
Zhengquan ZHANG
;
Cheng ZHANG
;
Deyuan FU
- Publication Type:Journal Article
- Keywords:
Wnt signaling pathway;
β-catenin;
Breast neoplasms
- From:
International Journal of Surgery
2015;42(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Wnt/β-catenin signaling pathway regulates cell proliferation,differentiation,and takes part in the process of gene expression and cell migration.The recent researches have shown that abnormal Wnt/β-catenin signal is closely related to the development of breast cancer and other tumors.Elucidation of the relationship between Wnt/β-catenin and breast cancer can help to reveal its mechanisms and provide a new insight into breast cancer prevention and treatment.Here,we summarize the latest advances about components and mechanism of Wnt/β-catenin pathway in breast cancer as below.
