A prospective clinical controlled study of retroperitoneal laparoscopic nephroureterectomy combined with transurethral electric coagulation for upper urinary tract urothelial carcinoma
10.3760/cma.j.issn.1000-6702.2014.12.006
- VernacularTitle:后腹腔镜下肾输尿管切除术联合经尿道电凝治疗上尿路尿路上皮癌的前瞻性临床对照研究
- Author:
Jiantao WANG
;
Chunhong ZHANG
;
Shengqiang YU
;
Ke WANG
;
Changping MEN
;
Zhenli GAO
- Publication Type:Journal Article
- Keywords:
Laparoscopes;
Upper urinary tract urothelial carcinoma;
Urinary bladder neoplasms;
Transurethral electric coagulation;
Controlled clinical trials
- From:
Chinese Journal of Urology
2014;35(12):905-908
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of retroperitoneal laparoscopic nephroureterectomy (RLNU) combined with transurethral electric coagulation on upper urinary tract urothelial carcinoma (UUTUC).Methods Sixty UUTUC patients were enrolled from Jun.2012 to Apr.2013.The prospective clinical controlled analysis method was adopted in this study.All patients were divided into test group and control group according to the order of admission.Thirty cases (test group) underwent RLNU combined with electric coagulation,and 30 cases (control group) underwent RLNU combined with electric resection.The differences in operation time,blood loss,hospital stay and tumor recurrence rate between the 2 groups were compared.Results All the 60 operations for UUTUC were successful without conversion to open surgery.No intraoperative complications such as great vessels or surrounding organs damage occurred.There were 2 cases loss to follow-up in test group and 3 cases in control group.There were no significant differences in operation time,blood loss,follow-up time,tumor stage and tumor grade between the 2 groups.The hospital stay in the test group was shorter (5.5±2.0 d versus 7.1±2.2 d),the tumor recurrence rate was lower [4% (1/28) versus 30% (8/27)],and the differences were significant (P<0.05).Conclusion Compared with RLNU combined with transurethral electric resection,RLNU combined with electric coagulation has advantages of shorter hospital stay and lower tumor recurrence rate.