Endoscopic Treatment of an Adult with Tegmental Astrocytoma Accompanied by Cerebrospinal Fluid Dissemination.
10.3340/jkns.2014.0808.026
- Author:
Runchun LU
1
;
Chuzhong LI
;
Xinsheng WANG
;
Yazhuo ZHANG
Author Information
1. Neurosurgical Department, Peking University First Hospital, Beijing, China.
- Publication Type:Case Report
- Keywords:
Neuroendoscope;
Astrocytoma;
Tegmentum;
Dissemination;
Biopsy
- MeSH:
Adult*;
Astrocytoma*;
Biopsy;
Cerebrospinal Fluid*;
Combined Modality Therapy;
Drug Therapy;
Female;
Glioma;
Humans;
Hydrocephalus;
Magnetic Resonance Imaging;
Mesencephalon;
Neoplasm Metastasis;
Neuroendoscopes;
Prognosis;
Radiotherapy;
Ventriculostomy
- From:Journal of Korean Neurosurgical Society
2017;60(3):375-379
- CountryRepublic of Korea
- Language:English
-
Abstract:
Midbrain gliomas are relatively rare neoplasms with a generally benign prognosis, with dissemination or metastasis not previously reported. We describe here a woman, in whom magnetic resonance imaging scans showed hydrocephalus and a tegmental lesion in the upper aqueduct. Endoscopic third ventriculostomy and biopsy were performed; during surgery, a second small lesion was observed in the infundibular recess. Histologically, the two lesions had the characteristics of low grade astrocytoma, suggesting that the midbrain astrocytoma may have been disseminated via the cerebral spinal fluid to the infundibular recess. Postoperatively this patient received radiotherapy for nearly one month. Although patients with these tumors are not usually administered adjunctive therapy, radiation and, combined modality therapy, including surgery, radiotherapy, and chemotherapy, may be beneficial in patients with midbrain gliomas with dissemination.
