Primary Glioblastoma of the Cerebellopontine Angle: Case Report and Review of the Literature.
10.3340/jkns.2015.0303.006
- Author:
Ji Hye LEE
1
;
Jong Hyun KIM
;
Taek Hyun KWON
Author Information
1. Department of Neurosurgery, VHS Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Glioblastoma multiforme;
Cerebellopontine angle;
Extraaxial
- MeSH:
Adult;
Aged;
Biopsy;
Cerebellopontine Angle*;
Cerebrum;
Diagnosis;
Diagnosis, Differential;
Drug Therapy;
Female;
Follow-Up Studies;
Gait;
Glioblastoma*;
Humans;
Magnetic Resonance Imaging;
Memory;
Petrous Bone
- From:Journal of Korean Neurosurgical Society
2017;60(3):380-384
- CountryRepublic of Korea
- Language:English
-
Abstract:
Glioblastoma multiforme (GBM) is located most frequently in the cerebral hemispheres. Glioblastoma presenting as an extraaxial mass of cerebellopontine angle (CPA) is very rare in adults. We report a rare case of GBM arising in the CPA. The patient was a 71-year-old female, who complained of progressive gait disturbance and poor memory. Initial magnetic resonance imaging (MRI) revealed a 1.4×1.3 cm mass in the left CPA, with broad base to the petrous bone, showing homogenous enhancement. Follow-up MRI showed a rapid increase in size of mass (2.7×2.2 cm) with a necrotic portion. A stereotactic biopsy was done under the guidance of navigation system, and the histopathologic diagnosis was GBM, World Heath Organization grade IV. Further surgical resection was not performed considering her general condition, and the patient underwent concurrent chemotherapy with radiation therapy. Although rare, the possibility of glioblastoma should be included in the differential diagnosis of atypical CPA tumor.
