Pathogenesis and interventions of cancer-related sarcopenia
10.3760/cma.j.issn.1674-635X.2015.03.012
- VernacularTitle:肿瘤相关性肌肉减少症的发病机制与干预措施
- Author:
Xiaoyan XUE
;
Qian LU
- Publication Type:Journal Article
- Keywords:
Tumor;
Sarcopenia;
Pathogenesis;
Intervention
- From:
Chinese Journal of Clinical Nutrition
2015;23(3):183-188
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of cancer-related sarcopenia is complicated,involving all aspects of tumor and the body's metabolism,mainly related to accelerated proteolysis and insufficient protein synthesis.Cancerrelated sarcopenia can predict antineoplastic-induced dose-limiting toxicities,increase complications,and reduce survival rate.The interventions of cancer-related sarcopenia includes nutrition,exercise,hormone therapy and other interventions.A single treatment can not reverse clinical outcome.Various interventions are still in the investigation stage,in which more evidence-based studies are needed.
