Replacement therapy of hypothyroidism: Whether the use of levothyroxine is adequate?
10.3760/cma.j.issn.1000-6699.2015.04.003
- VernacularTitle:甲状腺功能减退症替代治疗:使用左旋甲状腺素是否充足?
- Author:
Hui ZHU
;
Chao LIU
;
Keying CAI
- Publication Type:Journal Article
- Keywords:
Hypothyroidism;
Levothyroxine;
Combination therapy
- From:
Chinese Journal of Endocrinology and Metabolism
2015;31(4):296-299
- CountryChina
- Language:Chinese
-
Abstract:
Hypothyroidism is a common endocrine disease.Its treatment depends on thyroid hormone replacement therapy.Currently,levothyroxine (L-T4) is the preparation recommended by many guidelines.However,there are some L-T4-treated patients with normal TSH levels and persistent non-specific symptoms and discomforts.Therefore,combination therapy with L-T4and liothyronine (L-T3) has been considered as an alternative option for hypothyroidism.However,more prospective studies are needed to provide evidence-based effects for this kind of regimen.