Vitamin D nutrition status of 3 724 children of 0-6 years for routine physical examination in outpatient clinic in Huzhou
10.3760/cma.j.issn.1674-635X.2014.06.007
- VernacularTitle:湖州市3724例0～6岁门诊体检儿童维生素D营养状况
- Author:
Guoping SHEN
;
Dan BI
- Publication Type:Journal Article
- Keywords:
Infants;
25-hydroxy vitamin D;
Vitamin D level;
Vitamin D deficiency
- From:
Chinese Journal of Clinical Nutrition
2014;22(6):354-359
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate vitamin D nutrition of children aging 0-6 years who received routine physical checkup in outpatient clinic,and to provide evidence for supplementation of vitamin D.Methods A total of 3 724 children were enrolled in children healthcare outpatient clinic in the Maternity and Child Health Care Hospital of Huzhou from January 2013 to March 2014.Serum 25-hydroxy vitamin D [25-(OH) D] levels of the children were measured using electrochemiluminescence to compare serum 25-(OH) D levels and vitamin D deficiency in children of different ages and in seasons.Results The mean 25-(OH) D level in these children was (37.80 ± 11.67) ng/ml,and the prevalence of vitamin D deficiency was 7.33％,neither showing significant difference between boys and girls (t =-1.57,P =0.117 ; x2 ＝ 0.37,P =0.543).The serum 25-(OH) D level in ＞3-and-≤6 years group was remarkably lower than the levels in ≤1 year,＞ 1-and-≤2 years and ＞2-and-≤3 years groups [(27.36 ±8.90) ng/ml vs.(38.64 ± 12.10) ng/ml,t =18.60,P=0.000;vs.(41.63±10.31) ng/ml,t=26.07,P=0.000;vs.(36.85±10.01) ng/ml,t=16.42,P =0.000],and the prevalence of vitamin D deficiency significanl higher than those in the other 3 age groups (104/466 vs.122/1 487,x2 =69.06,P =0.000; vs.18/1 106,x2 =196.06,P =0.000; vs.29/665,x2 =85.14,P =0.000).The serum 25-(OH) D level in children in winter was significantly lower than in spring,summer,and autumn [(35.16 ± 11.30) ng/ml vs.(40.03 ± 12.57) ng/ml,t =9.15,P =0.000;vs.(36.86±10.60) ng/ml,t=3.34,P=0.001; vs.(39.99±11.36) ng/ml,t=9.65,P=0.000],and the prevalence of vitamin D deficiency significantly higher than in the other 3 seasons (127/1 189 vs.56/ 849,x2 =10.11,P =0.001; vs.54/787,x2 =28.30,P=0.004; vs.36/899,x2 =31.71,P=0.000).Conclusions Vitamin D nutrition status of infants at 0-6 years in our child healthcare outpatient clinic is generally good,except for lower vitamin D level and higher prevalence of vitamin D deficiency in winter and ＞3-and-≤6 years age group.Therefore,vitamin D supplementation in winter and in children above 3 years old is especially important.Recommendations include more outdoor activities and public education for scientific prevention of vitamin D deficiency.
