Clinical observation of early feeding tolerance to amino acid-based formula combined with rice oil in children with persistent diarrhea induced by cow's milk protein allergy
10.3760/cma.j.issn.1674-635X.2014.05.007
- VernacularTitle:氨基酸配方营养粉联合米油对牛奶蛋白过敏致迁延性腹泻患儿早期喂养耐受性的临床观察
- Author:
Junhong YANG
;
Ying LIN
;
Xi TIAN
;
Ping LI
;
Yingxin CHEN
;
Wenzhuo ZHAO
;
Dong AN
- Publication Type:Journal Article
- Keywords:
Amino acid-based formula;
Rice oil;
Infant;
Cow's milk protein allergy;
Persistent diarrhea
- From:
Chinese Journal of Clinical Nutrition
2014;22(5):288-292
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effects of amino acid-based formulae (AAF) combined with rice oil in treating children with persistent diarrhea caused by cow's milk protein allergy (CMPA).Methods We selected 60 infants (6-12 months) with CMPA-induced persistent diarrhea treated in Tianjin Children's Hospital between April 2011 and December 2013 and divided them into control group (n =30) and observation group (n =30) with a random number table.The control group was given AAF treatment,while the observation group was given the combination treatment of AAF + rice oil The two groups were compared in terms of treatment efficiency,period before improvement of stools,antidiarrheal time,early adverse reactions (vomit,abdominal distension),and the period before disappearance of systemic symptoms (frequent crying).Results The effective rate was 89.3％ in the control group and 96.7％ in the observation group,with no statistically significant difference (P =0.267).Adverse reactions disappeared significantly earlier in the observation group than in the control group [abdominal distension:(7.2 ± 1.7) days vs.(9.4 ±2.3) days; vomit:(8.6 ±2.5) days vs.(12.5 ±2.0) days; frequent crying:(8.0 ± 1.6) days vs.(10.0 ± 2.1) days; all P =0.000].Conclusions AAF is the first choice to treat CMPA-induced diarrhea.Early use of AAF in combination with rice oil could achieve better feeding tolerance in infant with CMPA-induced diarrhea.
