Serum concentration of B vitamins and their correlation to epilepsy
10.3760/cma.j.issn.1674-635X.2014.05.006
- VernacularTitle:血清B族维生素含量与癫痫相关性分析
- Author:
Jun LI
;
Jing LIU
;
Meiyan WU
;
Chao CHE
;
Xiuli JU
;
Baomin LI
- Publication Type:Journal Article
- Keywords:
Epilepsy;
Vitamin B1;
Vitamin B6;
Vitamin B12
- From:
Chinese Journal of Clinical Nutrition
2014;22(5):285-287
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of serum concentration of B vitamins B1,B6,B12) with the incidence of epilepsy.Methods We recruited 50 newly diagnosed patients with epilepsy (not receiving antiepileptic drugs) and 50 patients without epilepsy.Serum concentrations of B vitamins (B1,B6,and B12) in both groups were detected with a LK3000V vitamin detector.Results The concentrations of vitamin B1 and B12 in epileptic patients were (132.81 ±7.3l) nmol/L and (221.41 ±26.09) pg/ml,respectively,not significantly different from those in non-epileptic patients [(130.44 ± 5.12) nmol/L,P =0.095 ;(197.87 ± 19.36) pg/ml,P =0.077].The concentration of vitamin B6 in epileptic children was (44.61 ±2.49) μmol/L,significantly lower than that in non-epileptic children [(64.63 ± 5.71) μmol/L,P =0.031].Conclusion Though serum concentrations of vitamin B1 and B12 may not be associated with epilepsy,lower concentration of vitamin B6 in serum may increase the risk of epilepsy.
