Preoperative liver function analysis of 270 patients with laparoscopic common bile duct exploration
10.3760/cma.j.issn.1008-6706.2015.09.036
- VernacularTitle:腹腔镜胆总管探查患者270例术前肝功能指标分析
- Author:
Qiang LIU
- Publication Type:Journal Article
- Keywords:
Choledocholithiasis;
Liver function;
Laparoscopy;
Ultrasonography
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;22(9):1381-1384
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of liver function for cases of laparoscopic common bile duct exploration indications to identify the exploration negative and positive.Methods Grouped the 270 cases of laparoscopic common bile duct exploration according to the negative and positive exploration,analyzed differences between groups,analyzed diagnostic value of every index,and established scoring system and evaluate the diagnostic value.Results The liver function index ALT(P =0.003),AST (P =0.039),ALP(P ＜ 0.001),GGT (P ＜ 0.001),TB (P =0.031),DB (P =0.003),gender (P =0.002),ultrasound results (P =0.001) had differences between the groups.The best cutoff value index of liver function:ALT (33.5 U/L),AST (38.5 U/L) and ALP (87.5 U/L),GGT (34 U/L),TB (16.00 U mol/L),DB (4.00 U mol/L);The diagnostic value and the 95％ confidence interval for each indicator:ALT 0.649 (0.563 ～ 0.736),0.600 (0.510 ～ 0.691) AST,ALP 0.673 (0.596 ～ 0.750),GGT 0.674 (0.592 ～ 0.755),TB (0.489 ～ 0.656),0.572 DB 0.652 (0.568 ～ 0.737).The highest diagnostic value was value scoring system diagnosis,the diagnostic value of the best cutoff value and 95％ confidence interval were 0.741 (0.662 ～0.820).The positive predictive value was 70.2％,negative predictive value was 65.9％.Conclusion The scoring system with liver function,gender and ultrasound findings established chnical reference value for identifying those who do not need the common bile duct exploration from cases of laparoscopic common bile duct exploration indications.
