A nested case-control study of influencing factors of chronic brucellosis

VernacularTitle:布鲁杆菌病转为慢性影响因素的巢式病例对照研究
Author: Yue ZHAO ; Ying WANG ; Zhanli WANG ; Hui YU ; Chunfang LIU
Publication Type:Journal Article
Keywords: Brucellosis; Risk factors; Nested case-control study; Logistic regression
From: Chinese Journal of Endemiology 2015;34(6):450-451
CountryChina
Language:Chinese
Abstract: Objective To investigate the influencing factors of chronic brucellosis.Methods Nested case control method was used to study newly diagnosed patients (n =600) with brucellosis in a cohort study in 2012.Data of general characterstics,clinical presentation,treatment and prognosis of those patients were collected.These patients were followed up for one year,and the chronic patients as the case group (n =248) and the healed patients as a control group (n =260).By means of Logistic multivariate analysis,factors turned brucellosis into chronic were screened.Result The chronic brucellosis-related factors were:gender,veterinary or epidemic prevention staff,muscle and joint pain,fatigue symptoms,and substandard treatment (x2 =5.163,16.445,14.977,17.154,8.813,all P ＜ 0.05).Conclusion Gender (female),veterinary or epidemic prevention staff,muscle and joint pain,fatigue symptoms,and substandard treatment are probably the chronic brucellosis-related factors