A Case of Athyrotic Cretinism.
- Author:
Sang Chil YOON
1
;
Kil Woo KIM
;
Myoung Suk LEE
;
Churl Young CHUNG
;
Jong Eun JOO
;
Ill IIyang KO
Author Information
1. Department of Pediatrics, Paik Foundation Hospital, Seoul, Korea.
- Publication Type:Case Report
- MeSH:
Autopsy;
Congenital Hypothyroidism*;
Diagnosis;
Female;
Foot;
Hand;
Hernia, Umbilical;
Humans;
Hypothyroidism;
Infant;
Jaundice;
Lethargy;
Skin;
Thyroid Function Tests;
Thyroid Gland;
Tongue
- From:Journal of the Korean Pediatric Society
1978;21(9):594-599
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This paper presented a case of athyrotic cretinism in a 4 months old female infant. Durring neonatal 7 period she suffered from prolonged jaundice for about 50 days On admission, elinical manifestations suggesting of hypothyroidism were umbilical hernia, feeding problems due to large tongue, respiratory difficulty, lethargy and skin changes Roengenogram of the long bone series revealed the absence of epiphyseal centers of capitates and hamates in the hands, and cuboids in the feet. Thyroid function test also showed 6.5% and 4.1% at 6 hours and 24 hours after I131 uptake respectively, and T 3 value of 25.1ug/dl and T4 of 3.0ug/dl. On thyroid scan, no evidence of activity of thyroid gland was noted. Complete absence of thyroid tissues on autopsy of this baby confirmed the diagnosis of athyrotic cretinism. The review of the literature Concerning the Congenital hypothyroidism were made briefly.
