Sedation with oral or rectal chloral hydrate in pediatric patients:A Meta-analysis
10.3760/cma.j.issn.1672-7088.2014.31.018
- VernacularTitle:水合氯醛不同给药途径下儿童镇静效果比较的Meta分析
- Author:
Guojian DING
;
Xijie LIU
;
Chuanzhen XU
;
Lei GENG
;
Tingliang FU
- Publication Type:Journal Article
- Keywords:
Chloral hydrate;
Sedation;
Children
- From:
Chinese Journal of Practical Nursing
2014;30(31):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the sedative efficacy with oral or rectal chloral hydrate in pediatric patients by using Meta-analysis method.Methods Ten randomized controlled trials about the sedative efficacy with oral or rectal chloral hydrate in pediatric patients were retrieved.Meta-analysis was carried out using the RevMan 5.0 software.Results The results showed that the sedative efficacy with rectal medication was better than that with oral way.Nausea and vomiting occurred in 95 children with oral chloral hydrate,bowel movement occurred in 57 children with rectal chloral hydrate.Conclusions The sedative efficacy with rectal chloral hydrate was better than that with oral way.The safety in pediatric sedation with chloral hydrate should be emphasized in order to avoid adverse reaction.